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1,2-dioleoyl-3-trimethylammonium-propane (chloride salt)

1,2-dioleoyl-3-trimethylammonium-propane (chloride salt)

CAS: 132172-61-3

Molecular Formula: C42H80ClNO4

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1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) - Names and Identifiers

Name 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt)
Synonyms DOTMA
DOTAP
dotap chloride
DOTAP CHLORIDE SALT
1,2-DIOLEOYL-3-TRIMETHYLAMMONIUM-PROPANE, CHLORIDE
1,2-dioleoyl-3-trimethylammonium-propane (chloride salt)
N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE
N-[1-(2,3-DIOLEOYLOXY) PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE
N-[1-(2,3-DIOLEOYLOXY)PROPYL]-N,N,N-TRIMETHYL-AMMONIUM CHLORIDE SALT
CAS 132172-61-3

1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) - Physico-chemical Properties

Molecular FormulaC42H80ClNO4
Molar Mass698.54
Melting Point35-38°C
Solubility Chloroform (Slightly)
Appearancelyophilized powder
ColorWhite to Pale Yellow Low Melting Sticky
Storage Condition-20°C
StabilityStore in Freezer, Hygroscopic
In vitro study liposomes are reorganized by associating with DNA.ThetransfectionefficiencyofDOTAP liposomesis mainly influenced by lipid composition andcelltype, but not by size or zeta potential.

1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) - Risk and Safety

WGK Germany3

1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) - Reference Information

biological activity DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) is a potent Cationic lipid, it is widely used as a liposomal transfer reagent. DOTAP is also a strong activator of the innate immune system in animal cells and may serve as a potential candidate for the Study of initiators of plant immunity.
Target IC50: Cationic Lipid
Last Update:2024-04-09 20:45:29
1,2-dioleoyl-3-trimethylammonium-propane (chloride salt)
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CAS: 132172-61-3
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View History
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